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MED-LIFE DISCOVERIES
Plasmalogens
RCDP
Neurological
MED-LIFE DISCOVERIES
Plasmalogens
RCDP
Neurological
Plasmalogens
RCDP
Neurological
Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells.
Kaeli Knudsen 4/22/21 Kaeli Knudsen 4/22/21

Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells.

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Anti-inflammatory/anti-amyloidogenic effects of plasmalogens in lipopolysaccharide-induced neuroinflammation in adult mice
Kaeli Knudsen 4/8/21 Kaeli Knudsen 4/8/21

Anti-inflammatory/anti-amyloidogenic effects of plasmalogens in lipopolysaccharide-induced neuroinflammation in adult mice

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Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
Kaeli Knudsen 3/25/21 Kaeli Knudsen 3/25/21

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

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Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes
Kaeli Knudsen 3/10/21 Kaeli Knudsen 3/10/21

Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes

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Change in brain plasmalogen composition by exposure to prenatal undernutrition leads to behavioral impairment of rats.
Kaeli Knudsen 2/18/21 Kaeli Knudsen 2/18/21

Change in brain plasmalogen composition by exposure to prenatal undernutrition leads to behavioral impairment of rats.

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Distinct functions of acyl/alkyl dihydroxyacetonephosphate reductase in peroxisomes and endoplasmic reticulum
Kaeli Knudsen 2/4/21 Kaeli Knudsen 2/4/21

Distinct functions of acyl/alkyl dihydroxyacetonephosphate reductase in peroxisomes and endoplasmic reticulum

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Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosis
Kaeli Knudsen 1/20/21 Kaeli Knudsen 1/20/21

Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosis

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How do ethanolamine plasmalogens contribute to order and structure of neurological membranes?
Kaeli Knudsen 1/7/21 Kaeli Knudsen 1/7/21

How do ethanolamine plasmalogens contribute to order and structure of neurological membranes?

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The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations
Kaeli Knudsen 12/17/20 Kaeli Knudsen 12/17/20

The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations

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Impaired membrane traffic in defective ether lipid biosynthesis
Kaeli Knudsen 12/10/20 Kaeli Knudsen 12/10/20

Impaired membrane traffic in defective ether lipid biosynthesis

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Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease
Kaeli Knudsen 12/3/20 Kaeli Knudsen 12/3/20

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease

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Plasmenylethanolamine facilitates rapid membrane fusion
Kaeli Knudsen 11/26/20 Kaeli Knudsen 11/26/20

Plasmenylethanolamine facilitates rapid membrane fusion

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Oral administration of ethanolamine glycerophospholipid containing a high level of plasmalogen improves memory impairment in amyloid β-infused rats
Kaeli Knudsen 11/12/20 Kaeli Knudsen 11/12/20

Oral administration of ethanolamine glycerophospholipid containing a high level of plasmalogen improves memory impairment in amyloid β-infused rats

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Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder
Kaeli Knudsen 10/29/20 Kaeli Knudsen 10/29/20

Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder

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Disturbed neurotransmitter homeostasis in ether lipid deficiency
Kaeli Knudsen 10/15/20 Kaeli Knudsen 10/15/20

Disturbed neurotransmitter homeostasis in ether lipid deficiency

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Nrf2 suppresses oxidative stress and inflammation in App knock-in Alzheimer’s disease model mice
Kaeli Knudsen 10/1/20 Kaeli Knudsen 10/1/20

Nrf2 suppresses oxidative stress and inflammation in App knock-in Alzheimer’s disease model mice

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Structural changes of ethanolamine plasmalogen during intestinal absorption
Kaeli Knudsen 9/17/20 Kaeli Knudsen 9/17/20

Structural changes of ethanolamine plasmalogen during intestinal absorption

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Digestion, absorption, and metabolism characteristics of EPA-enriched phosphoethanolamine plasmalogens based on gastrointestinal functions in healthy mice
Kaeli Knudsen 9/3/20 Kaeli Knudsen 9/3/20

Digestion, absorption, and metabolism characteristics of EPA-enriched phosphoethanolamine plasmalogens based on gastrointestinal functions in healthy mice

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Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids
Kaeli Knudsen 8/20/20 Kaeli Knudsen 8/20/20

Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids

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Oral batyl alcohol supplementation rescues decreased cardiac conduction in ether phospholipid-deficient mice.
Kaeli Knudsen 7/31/20 Kaeli Knudsen 7/31/20

Oral batyl alcohol supplementation rescues decreased cardiac conduction in ether phospholipid-deficient mice.

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